Changes in Sleep-Wakefulness after Kainic Acid Lesion of the Preoptic Area in Rats.
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چکیده
منابع مشابه
Effect of Lateral Preoptic Area Lesion on Sleep Wakefulness and Thermoregulation In Cold Acclimatized Rats
Hypothalamic temperature (Thy) alteration is one of the important stimuli that brings about thermoregulatory measures including the changes in wakefulness and muscular activity. The role of the lateral preoptic area (lPOA) in thermoregulation and sleep is well documented. But it is not known whether the integrity of the lPOA is essential for bringing about the changes in sleep-wakefulness (S-W)...
متن کاملEffect of ambient temperature on brain temperature and sleep-wakefulness in medial preoptic area lesioned rats.
The changes in brain temperature and sleep-wakefulness were studied in rats during their exposure to different ambient temperatures of 18 degrees C, 24 degrees C and 30 degrees C, before and after N-methyl D-aspartic acid lesion of the medial preoptic area. The medial preoptic area lesion produced a decrease in sleep, and increase in brain temperature except at 30 degrees C. Increase and decrea...
متن کاملEffect of application of gamma amino butyric acid at the medial preoptic area on sleep-wakefulness.
Intracerebral microinjections of gamma amino butyric acid were given bilaterally at the medial preoptic area (mPOA) to determine the possible role of this neurotransmitter in the genesis and regulation of sleep-wakefulness. GABA (50 micrograms/0.2 microliters) when administered through chronically implanted cannulae in free moving rats, did not produce any significant alterations in sleep-wakef...
متن کاملEffects of gamma-aminobutyric acid A-receptor antagonist on sleep-wakefulness cycles following lesion to the ventrolateral preoptic area in rats*
BACKGROUND: Neurons expressing gamma-aminobutyric acid (GABA) play an important role in the regulation of wakefulness to sleep, as well as the maintenance of sleep. However, the role of GABAergic neurons in the tuberomammillary nucleus (TMn), with regard to the sleep-wakefulness cycle, is poorly understood. OBJECTIVE: To investigate the effects of GABAergic neurons in the TMn on the sleep-wakef...
متن کاملEffect of carbachol injection in the medial preoptic area on sleep-wakefulness and body temperature in free moving rats.
The aim of the present study was to find out the changes in sleep-wakefulness and body temperature brought about by application of cholinergic agonist, carbachol, in the medial preoptic area (mPOA). Carbachol, when injected bilaterally into the mPOA of male rats, through chronically implanted cannulae, produced a fall in rectal temperature and long lasting arousal. There was temporal dissociati...
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ژورنال
عنوان ژورنال: The Japanese Journal of Physiology
سال: 1994
ISSN: 0021-521X
DOI: 10.2170/jjphysiol.44.231