Changes in Pulmonary Vascular Resistance in Infants and Children with Left-to-Right Intracardiac Shunts

Changes in Pulmonary Vascular Resistance in Infants and Children with Left-to-right Intracardiac Shunts.

Radionuclide quantitation of right-to-left intracardiac shunts in children.

A simple, noninvasive method for measurement of right-to-left intracardiac shunts would enhance the management of patients with congenital heart disease. This study describes application of data processing techniques used previously in dye-indicator curves to data recorded during the initial transit of radioactive bolus through the central circulation. Radionuclide angiocardiograms were perform...

Oximetric detection of intracardiac left-to-right shunts.

To assess prevailing guidelines for the oximetric detection of intracardiac left-to-right shunts, we examined the variability of right heart oxygen saturation step-ups in 1121 catheterisations in children with aortic and pulmonary stenosis, who were studied as part of the joint study of the natural history of congenital heart defects. It is estimated that in the absence of intracardiac shunting...

Left-to-Right Shunts

Contrary to the opinion of French pediatrician HenriLouis that isolated ventricular septal defects (VSDs) are universally well tolerated, the subsequent discoveries of Eisenmenger, Abbott, Wood, and others have taught us that the prognosis of left-to-right shunt lesions is not always benign. After more than a century of research, as pediatric cardiologists and congenital heart surgeons, we clai...

Perflutren-based echocardiographic contrast in patients with right-to-left intracardiac shunts.

septum length, and rims and thickness with electronic caliper edgeto-edge (4). Four main features were used to analyze patients: 1) diameter of the fossa ovalis (FO); 2) presence and length of the channel; 3) presence and degree of atrial septal aneurysm (ASA), following the classification of Olivares et al. (5); and 4) rim thickness. We also analyzed the presence of Eustachian valve and Chiari...