Changes in motoneuron excitability during voluntary muscle activity in humans with spinal cord injury
نویسندگان
چکیده
منابع مشابه
Adrenergic receptors modulate motoneuron excitability, sensory synaptic transmission and muscle spasms after chronic spinal cord injury.
The brain stem provides most of the noradrenaline (NA) present in the spinal cord, which functions to both increase spinal motoneuron excitability and inhibit sensory afferent transmission to motoneurons (excitatory postsynaptic potentials; EPSPs). NA increases motoneuron excitability by facilitating calcium-mediated persistent inward currents (Ca PICs) that are crucial for sustained motoneuron...
متن کاملMuscle Spasms After Chronic Spinal Cord Injury Excitability, Sensory Synaptic Transmission and Adrenergic Receptors Modulate Motoneuron
[PDF] [Full Text] [Abstract] , April , 2011; 105 (4): 1835-1849. J Neurophysiol Brian R. Noga, Dawn M. G. Johnson, Mirta I. Riesgo and Alberto Pinzon receptors in the thoraco-lumbar spinal cord 2b α or NE 1a α with NE Locomotor-activated neurons of the cat. II. Noradrenergic innervation and colocalization [PDF] [Full Text] [Abstract] , October , 2011; 106 (4): 1652-1661. J Neurophysiol Tany...
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This study of chronic incomplete spinal cord injury (SCI) subjects investigated patterns of central motor drive (i.e., central activation) of the plantar flexors using interpolated twitches, and modulation of soleus H-reflexes during lengthening, isometric, and shortening muscle actions. In a recent study of the knee extensors, SCI subjects demonstrated greater central activation ratio (CAR) va...
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BACKGROUND From the onset to the chronic phase of spinal cord injury (SCI), peripheral axons and muscles are subjected to abnormal states of activity. This starts with very intense spasms during the first instant of SCI, through a no activity flaccidity phase, to a chronic hyperactivity phase. It remains unclear how the nature of this sequence may affect the peripheral axons and muscles. METH...
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Intensive treadmill training after incomplete spinal cord injury can improve functional walking abilities. To determine the changes in muscle activation patterns that are associated with improvements in walking, we measured the electromyography (EMG) of leg muscles in 17 individuals with incomplete spinal cord injury during similar walking conditions both before and after training. Specific dif...
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ژورنال
عنوان ژورنال: Journal of Neurophysiology
سال: 2020
ISSN: 0022-3077,1522-1598
DOI: 10.1152/jn.00367.2019