منابع مشابه
Chromatin structure and transposable elements in organismal aging
Epigenetic regulatory mechanisms are increasingly appreciated as central to a diverse array of biological processes, including aging. An association between heterochromatic silencing and longevity has long been recognized in yeast, and in more recent years evidence has accumulated of age-related chromatin changes in Caenorhabditis elegans, Drosophila, and mouse model systems, as well as in the ...
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The increasing consumption of energy from fossil fuels on the one hand and the pollution created by it on the other hand has always raised the concern of replacing clean and renewable energy with fossil fuels in the human mind. Generating electricity through clean energy can be a good solution to reduce pollutants and prevent global warming. One of the most available types of renewable energy i...
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Single-molecule experiments show that the chromatin-remodeling complex RSC, a member of the SNF2 ATPase family, induces formation of a negatively supercoiled DNA loop by active translocation.
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UNLABELLED Muscle physiology in the aging athlete is complex. Sarcopenia, the age-related decrease in lean muscle mass, can alter activity level and affect quality of life. This review addresses the microscopic and macroscopic changes in muscle with age, recognizes contributing factors including nutrition and changes in hormone levels, and identifies potential pharmacologic agents in clinical t...
متن کاملAbstract: Chromatin Structure Regulation in Human Adipose-Derived Stem Cell Aging
INTRODUCTION: Aging and age-related diseases have been linked to both genetic and epigenetic changes. The chromatin structure is critical to the transmission of epigenetic information impacting transcription and genomic stability. Adult stem cells play a pivotal role in the maintenance of tissue and organ homeostasis during aging and are frequently exploited in regenerative medicine and plastic...
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ژورنال
عنوان ژورنال: Journal of Gerontology & Geriatric Research
سال: 2014
ISSN: 2167-7182
DOI: 10.4172/2167-7182.1000157