Chagas' heart disease

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Chagas Heart Disease

Chagas disease (CD) or American trypanosomiasis is a complex zoonosis produced by the infection with the intracellular protozoan parasite Trypanosoma cruzi. Although the disease was first described in 1909 by the Brazilian physician Carlos Chagas, this disease affects human beings since antiquity as it was demonstrated by paleoparasitology studies which proved the presence of DNA in mummies dat...

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Heart Rate Variability and Chagas Heart Disease

Mailing Address: Marcos Antonio Almeida Santos • Avenida Gonçalo Prado Rollemberg, 211, sala 210, São José. Postal Code 49010‐410, Aracaju, SE – Brazil. E‐mail: [email protected]; [email protected] Manuscript received October 09, 2014; revised manuscript November 13, 2014; accepted November 13, 2014.

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Echocardiography in Chagas heart disease.

BACKGROUND Chagas heart disease is a frequent cause of morbidity and mortality in Latin America. Echocardiography provides useful diagnostic and prognostic information and is an important tool in the management of patients with Chagas disease. METHODS AND RESULTS A search for relevant publications was obtained from MEDLINE, LILACS, and SCIELO sources. Acute Chagas myocarditis is a rare disord...

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Autoimmunity in Chagas heart disease.

The possibility that cardiac autoimmunity contributes to the pathogenesis of Chagas heart disease is controversial. In this paper, we address the following questions regarding the genesis of autoimmunity in Chagas heart disease: (i) What mechanism(s) are potentially responsible for the generation of self-directed antibodies and lymphocytes? (ii) What is the evidence that any of these mechanisms...

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Epidemiology of Chagas' heart disease.

Chagas' disease is a major public health problem in Latin America. About 16 million persons are affected and 90 million others are exposed to the risk of being infected by the parasite. The knowledge of epidemiological aspects of the disease allowed to delineate the strategies for the control of the disease related with the vectorial transmission. However, these strategies have had no priority ...

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ژورنال

عنوان ژورنال: Arquivos Brasileiros de Cardiologia

سال: 1999

ISSN: 0066-782X

DOI: 10.1590/s0066-782x1999000300001