Cerebrospinal fluid markers for AD change during middle age
نویسندگان
چکیده
منابع مشابه
Longitudinal Cerebrospinal Fluid Biomarker Changes in Preclinical Alzheimer Disease During Middle Age.
IMPORTANCE Individuals in the presymptomatic stage of Alzheimer disease (AD) are increasingly being targeted for AD secondary prevention trials. How early during the normal life span underlying AD pathologies begin to develop, their patterns of change over time, and their relationship with future cognitive decline remain to be determined. OBJECTIVE To characterize the within-person trajectori...
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ژورنال
عنوان ژورنال: Nature Reviews Neurology
سال: 2015
ISSN: 1759-4758,1759-4766
DOI: 10.1038/nrneurol.2015.129