منابع مشابه
[Cerebral microdialysis in the current clinical setting].
Cerebral microdialysis, introduced in experimental studies 40 years ago, has been used clinically since 1992 for the neurochemical monitoring of patients in intensive care. The principles underlying this technique are closely related to brain metabolism. The study of the metabolites detected at brain interstitial tissue level, through the semipermeable membrane of the device, allows us to asses...
متن کاملCerebral microdialysis: research technique or clinical tool.
Cerebral microdialysis is a well-established laboratory tool that is increasingly used as a bedside monitor to provide on-line analysis of brain tissue biochemistry during neurointensive care. This review describes the principles of cerebral microdialysis and the rationale for its use in the clinical setting, including discussion of the most commonly used microdialysis biomarkers of acute brain...
متن کاملCerebral microdialysis: perioperative monitoring and treatment of severe neurosurgical patient.
The early signs of brain ischemia are key indicators of secondary brain injury and their recognition on time can ultimately save life. Direct recording of cerebral ischemia is possible using the method of cerebral microdialysis (CM). This paper presents results of the five-year experience in applying this method at University Department of Neurosurgery, Sarajevo University Clinical Center in Sa...
متن کاملAnalyses of cerebral microdialysis in patients with traumatic brain injury: relations to intracranial pressure, cerebral perfusion pressure and catheter placement
BACKGROUND Cerebral microdialysis (MD) is used to monitor local brain chemistry of patients with traumatic brain injury (TBI). Despite an extensive literature on cerebral MD in the clinical setting, it remains unclear how individual levels of real-time MD data are to be interpreted. Intracranial pressure (ICP) and cerebral perfusion pressure (CPP) are important continuous brain monitors in neur...
متن کاملRegional brain extracellular markers of cerebral ischaemia after aneurysmal subarachnoid haemorrhage: a combined cerebral microdialysis and perfusion CT study.
Methods We analyzed 48 PCT from 20 SAH patients (age 59 ± 8 years, median WFNS 4 [interquartile range 3-5]) monitored with CMD (in apparently normal brain) as part of standard care. PCT was categorized as ischemic (cerebral blood flow [CBF] < 32.5 mL/100g/min with a mean transit time >5.7 sec) vs. non-ischemic. Cerebral extracellular levels of lactate/pyruvate ratio (LPR) >40 with glucose < 1.0...
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ژورنال
عنوان ژورنال: Journal of Neuroanaesthesiology and Critical Care
سال: 2015
ISSN: 2348-0548,2348-926X
DOI: 10.4103/2348-0548.165049