Cerebral blood flow is regulated by changes in blood pressure and in blood viscosity alike.

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Cerebral blood flow is regulated by changes in blood pressure and in blood viscosity alike.

There is still considerable controversy regarding the influence of blood viscosity upon CBF. We have measured CBF with microspheres in 23 cats. Autoregulation was disturbed in the left caudate nucleus by microsurgical occlusion of the left middle cerebral artery. Induced hypertension or hypotension was used and i.v. mannitol (1 g/kg) administered. In all cats blood viscosity decreased an averag...

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Whole blood viscosity and cerebral blood flow.

BLOOD has anomalous rheological properties, particularly in certain disease states. It may therefore be necessary to consider these properties when attempting to assess and perhaps to improve the state of a patient's cerebral circulation. So what evidence is there that cerebral blood flow (CBF) is affected by viscosity? Before attempting to answer this question, one should be aware of what infl...

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Whole blood viscosity parameters and cerebral blood flow.

This report describes the statistical relationship of several whole blood viscosity parameters and cerebral blood flow (CBF) in 53 consecutive patients and normal controls. Significant correlations were present between CBF and serum fibrinogen (P = .05), hematocrit (P less than .05), and a relationship involving both fibrinogen and hematocrit (P less than .01). We conclude that heightened whole...

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Oxygen content, blood viscosity, and cerebral blood flow.

329 stated that "The model was soon found to be unreliable, perhaps due to failure to document a lack of brain blood flow during the ischemic period and to nonstandardized postischemic supportive care, aspects of peri-ischemic handling that were not appreciated at this time." In fact, the model itself was never unreliable, as the results in our first report showed.' Indeed, in developing the mo...

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ژورنال

عنوان ژورنال: Stroke

سال: 1986

ISSN: 0039-2499,1524-4628

DOI: 10.1161/01.str.17.1.44