منابع مشابه
Cerebellar Alterations in the Weaver Mouse
The fine structure of the cerebellum of weaver mouse was examined and the paucity of granule cells and their axons, the parallel fibers, was confirmed. Unexpectedly, however, the dendritic spines of the Purkinje cells which, in normal animals, are the postsynaptic mates of the parallel fibers, were present. Furthermore, their essential morphology and their staining reactions were indistinguisha...
متن کاملDefects in specific associations between astroglia and neurons occur in microcultures of weaver mouse cerebellar cells.
The neurological mutation weaver is characterized by defects in granule cell migration along Bergmann glial processes and by subsequent death and disposition of granule cells. Immunocytochemical localization of antisera raised against purified glial filament protein (AbGF) and transmission electron microscopy were used to visualize specific associations between granule neurons and astroglia in ...
متن کاملWeaver mouse cerebellar granule neurons fail to migrate on wild-type astroglial processes in vitro.
To study the regulation of glial-guided neuronal migration, we have analyzed the behavior of cerebellar granule neurons purified from the homozygous weaver (wv/wv) B6CBA-w mouse, an autosomal recessive genetic mutation that suffers a failure of granule cell migration along Bergmann glial processes (Rakic and Sidman, 1973a, b; Rezai and Yoon, 1972), on the processes of astroglia purified from ho...
متن کاملRadiation and cadmium induced biochemical alterations in mouse kidney
Background: In the present investigation radiation and cadmium induced biochemical changes in the kidney of Swiss albino mice have been studied. Materials and Methods: For this purpose, adult male Swiss albino mice (6-8 weeks old) were divided into four groups. Group I (sham-irradiated), Group II (treated with CdCl2 solution 20 ppm), Group III (irradiated with 1.25, 2.5 and 5.0 Gy gamma rays), ...
متن کاملImmunohistochemical studies on synapse formation by embryonic cerebellar tissue transplanted into the cerebellum of the weaver mutant mouse.
Normal cerebellar tissue, obtained from 15-day-old CBA/JNCij mouse embryos, was transplanted into the cerebellum of 4-week-old weaver mice. At the 6th week after the transplantation, the grafted tissue was distinguishable from the host cerebellum, developing a trilaminar organization. The formation of synapses by the implanted granule cells was analyzed immunohistochemically with antiserum agai...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 1973
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.56.2.478