Central role of Th2/Tc2 lymphocytes in pattern II multiple sclerosis lesions

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Central role of Th2/Tc2 lymphocytes in pattern II multiple sclerosis lesions

OBJECTIVE Multiple sclerosis (MS) is a disease of the central nervous system with marked heterogeneity in several aspects including pathological processes. Based on infiltrating immune cells, deposition of humoral factors and loss of oligodendrocytes and/or myelin proteins, four lesion patterns have been described. Pattern II is characterized by antibody and complement deposition in addition to...

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ژورنال

عنوان ژورنال: Annals of Clinical and Translational Neurology

سال: 2015

ISSN: 2328-9503,2328-9503

DOI: 10.1002/acn3.218