منابع مشابه
Central pontine myelinolysis.
Central pontine myelinolysis (CPM), a neurologic disorder caused most frequently by rapid correction of hyponatremia, is characterized by demyelination that affects the central portion of the base of the pons. There are no inflammatory changes, and blood vessels are normal. Clinical features usually reflect damage to the descending motor tracts and include spastic tetraparesis, pseudobulbar par...
متن کاملCentral pontine myelinolysis.
To cite: Grech R, Galvin L, Brennan P, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2013008920 DESCRIPTION Case report A 56-year-old gentleman was referred to the A&E department following an episode of loss of consciousness. His medical and surgical history was unremarkable except for a background history of alcohol dependency. Serological tests revealed...
متن کاملCentral pontine myelinolysis
Introduction Central pontine myelinolysis (CPM) in alcoholics and malnourished patients was first described by Adams, Victor and Mancall in 1959. This commonly fatal demyelinative process that involves the pons almost exclusively, is of unknown aetiology. In the majority of the published cases, CPM was associated with chronic alcoholism, malnutrition and electrolyte abnormalities, particularly ...
متن کاملCentral pontine myelinolysis.
The case is described of a 46 year old female alcoholic, presenting with confusion, jaundice and reduced level of consciousness. The patient was hyponatraemic on admission and despite gradual correction of serum sodium the patient deteriorated neurologically. Magnetic Resonance Imaging scan of the brain revealed characteristic findings of Central Pontine Myelinolysis (CPM). We provide an overvi...
متن کاملCentral pontine myelinolysis.
In 1949, Victor and Adams observed an alcoholic patient who developed quadriplegia and pseudobulbar palsy, and inability to chew, talk or swallow. A post-mortem confirmed their suspicion of 'a large, symmetrical, essentially demyelinative lesion occupying the greater part of the basis pontis.' This paper follows the historical evolution of central pontine myelinolysis and the changing concepts ...
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ژورنال
عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry
سال: 1964
ISSN: 0022-3050
DOI: 10.1136/jnnp.27.4.317