Celsior Preserved Cardiac Mechanoenergetics Better Than Popular Solutions in Canine Hearts
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Background. The aim of this experimental study was to compare the protective efficacy of the cardioplegic solutions Celsior and Custodiol. Canine hearts were examined with regard to energy metabolism and early postischemic recovery after 8 or 12 hours of ischemia at 5°C. Methods. Canine hearts were preserved with Celsior or Custodiol (each n 19). Five hearts of each group were used to determine...
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T he Respiratory Intensive Care Assembly at the European Respiratory Society (ERS) is composed of two areas of interest: noninvasive ventilation and acute critical care. Both of them are mainly focused on respiratory issues related to critically ill patients, aiming to promote the exchange of information between pneumonologists and intensivists, and to foster and encourage education, research a...
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Background. Most positive inotropic agents increase cardiac contractility by increasing the amount of Ca2 cycled with each beat. The additional amount of oxygen that is consumed by the heart to cycle this additional Ca2' is believed to reduce myocardial efficiency. On the other hand, it has been suggested that the agent EMD-53998 increases the Ca2' sensitivity of the contractile proteins withou...
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BACKGROUND Increasing allograft ischemic time is a significant risk factor for mortality following heart transplantation (HTx). The purpose of this study was to evaluate the protective effects of histidine-tryptophan-ketoglutarate (HTK) and Celsior (CEL) using a rat HTx model with prolonged cold storage. METHODS The hearts were excised from donor rats, stored in cold preservation solution for...
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ژورنال
عنوان ژورنال: The Annals of Thoracic Surgery
سال: 2006
ISSN: 0003-4975
DOI: 10.1016/j.athoracsur.2005.07.067