Cellular mechanisms of renal osteodystrophy
نویسندگان
چکیده
منابع مشابه
Renal osteodystrophy.
The incidence of chronic renal disease is increasing, and the pattern of renal osteodystrophy seems to be shifting from the classic hyperparathyroid presentation to one of low bone turnover. Patients with persistent disease also live longer than previously and are more physically active. Thus, patients may experience trauma as a direct result of increased physical activity in a setting of weake...
متن کامل201 - Renal osteodystrophy
2013 whose GFR is reduced due to intrinsic parenchymal damage as opposed to age-related reductions in GFR without another specific intrinsic renal diagnosis. At each level of CKD there may exist a specific form of renal osteodystrophy. The earliest form of renal bone disease (secondary hyperparathyroidism) may be defined by quantitative histomorphometry and/or biochemical profiling (elevated 1-...
متن کامل[Renal osteodystrophy and secondary hyperparathyroidism].
High-turnover bone due to excess PTH is one of the main types of renal osteodystrophy. In addition to the classic stimuli of PTH secretion such as hypocalcemia and decreased production of active vitamin D, new mechanisms has been suggested. Furthermore, skeletal resistance to PTH, a classic stimulus of PTH secretion in uremia, has been recently revisited as an underlying abnormality.
متن کاملSlipped epiphyses in renal osteodystrophy.
Clinical, biochemical, roentgenological, and histological features of slipped epiphyses (epiphysiolysis) in 11 out of 112 children with renal osteodystrophy have been analysed. Characteristic age-related patterns of involvement of different epiphyses are described. Quantitative measurements of iliac bone histology, serum parathyroid hormone levels, and clinical history show the presence of more...
متن کاملAlkali treatment of renal osteodystrophy.
In 1960 a 5-year-old girl was found to have developed accelerated hypertension (B.P. 190/150) with blood urea 119 mg/ 100 ml. An intravenous pyelogram showed a small scarred left kidney (5-3 by 32 cm). There was also upper pole scarring with clubbed calyces on the right side. Left nephrectomy was performed and histological examination of the kidney confirmed pyelonephritic changes, and showed i...
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ژورنال
عنوان ژورنال: Kidney International
سال: 1999
ISSN: 0085-2538
DOI: 10.1046/j.1523-1755.1999.07312.x