Cell Polarity and Development
نویسندگان
چکیده
منابع مشابه
Apicobasal polarity and cell proliferation during development.
Cell polarization and cell division are two fundamental cellular processes. The mechanisms that establish and maintain cell polarity and the mechanisms by which cells progress through the cell cycle are now fairly well understood following decades of experimental work. There is also increasing evidence that the polarization state of a cell affects its proliferative properties. The challenge now...
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Neurons populating the cerebral cortex are generated during embryonic development from neural stem and progenitor cells in a process called neurogenesis. Neural stem and progenitor cells are classified into several classes based on the different location of mitosis (apical or basal) and polarity features (bipolar, monopolar and non-polar). The polarized architecture of stem cells is linked to t...
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The polarization of the embryonic axes is a key event in embryogenesis, being one of the earliest manifestations of the shape and form of the organism. The acquisition of polarity by individual blastomeres is one of the earliest indicators of commitment t o a particular pathway of differentiation. These phenomena have been studied in the development of C. elegans both at the cellular and organi...
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In 1963, Sydney Brenner realized that “Part of the success of molecular genetics was due to the use of extremely simple organisms which could be handled in large numbers: bacteria and bacterial viruses.” He further argued “.....that the future of molecular biology lies in the extension of research to other fields of biology, notably development and the nervous system”. Thus, he proposed to the ...
متن کاملDLG5 in Cell Polarity Maintenance and Cancer Development
Failure in establishment and maintenance of epithelial cell polarity contributes to tumorigenesis. Loss of expression and function of cell polarity proteins is directly related to epithelial cell polarity maintenance. The polarity protein discs large homolog 5 (DLG5) belongs to a family of molecular scaffolding proteins called Membrane Associated Guanylate Kinases (MAGUKs). As the other family ...
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ژورنال
عنوان ژورنال: Journal of Integrative Plant Biology
سال: 2013
ISSN: 1672-9072
DOI: 10.1111/jipb.12099