منابع مشابه
Metabolomics and Cell Therapy in Diabetes Mellitus
Diabetes with a broad spectrum of complications has become a global epidemic metabolic disorder. Till now, several pharmaceutical and non-pharmaceutical therapeutic approaches were applied for its treatment. Cell-based therapies have become promising methods for diabetes treatment. Better understanding of diabetes pathogenesis and identification of its specific biomarkers along with evaluation ...
متن کاملSingle cell metabolomics.
Recent discoveries suggest that cells of a clonal population often display multiple metabolic phenotypes at the same time. Motivated by the success of mass spectrometry (MS) in the investigation of population-level metabolomics, the analytical community has initiated efforts towards MS-based single cell metabolomics to investigate metabolic phenomena that are buried under the population average...
متن کاملMetabolomics.
Metabolomics is based on the simultaneous analysis of multiple low-molecular-weight metabolites from a given sample. The goals of metabolomics are to catalog and quantify the myriad small molecules found in biological fluids under different conditions. The metabolomics represents the collection of all metabolites in a biological organism, and metabolic profiling can give an instantaneous 'snaps...
متن کاملMetabolomics guides rational development of a simplified cell culture
31 32 In vitro culture methods underpin many experimental approaches to biology and drug 33 discovery. The modification of established cell culture methods to be more 34 biologically relevant, or to optimise growth, is traditionally a laborious task. 35 Emerging metabolomics technology enables rapid evaluation of intraand extra36 cellular metabolites, and can be applied to the rational developm...
متن کاملMetabolomics of ADSOL (AS-1) red blood cell storage.
Population-based investigations suggest that red blood cells (RBCs) are therapeutically effective when collected, processed, and stored for up to 42 days under validated conditions before transfusion. However, some retrospective clinical studies have shown worse patient outcomes when transfused RBCs have been stored for the longest times. Furthermore, studies of RBC persistence in the circulati...
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ژورنال
عنوان ژورنال: OMICS: A Journal of Integrative Biology
سال: 2013
ISSN: 1536-2310,1557-8100
DOI: 10.1089/omi.2012.0090