Cell Free Fetal DNA: Marker for Predicting Pregnancy Outcomes
نویسندگان
چکیده
منابع مشابه
Introducing a New and Simple Protocol for Capillary Electrophoresis of Cell Free Fetal Double Stranded DNA
Isolation of cell free fetal DNA (cffDNA) from maternal serum usually leads to very low concentrations of DNA impeding further resolving through conventional methods of electrophoresis. Although several protocols have been described for capillary electrophoresis (CE) of double stranded DNA, they usually need using special polymers or coated capillaries which degrade over time. Herein, we propos...
متن کاملCell-free fetal DNA and pregnancy-related complications (Review)
Cell‑free fetal DNA (cff‑DNA) is a novel promising biomarker that has been applied in various aspects of obstetrical research, notably in prenatal diagnosis and complicated pregnancies. It is easily detected by semi‑quantitative PCR for the SRY target gene. It is well recognized that the levels of circulating cff‑DNA play a role in various complications of pregnancy. In this review, we explore ...
متن کاملZinc Deficiency in Pregnancy and Fetal - Neonatal Outcomes and Impact of the Supplements on Pregnancy Outcomes
Abstract Zinc is one of the essential elements of body which has an important role in natural growth, development, and many biological performances. Zinc deficiency is a major health problem and pregnant women are at high risk. 82% of pregnant women worldwide suffer from zinc deficiency. Zinc deficiency during pregnancy has dangerous and irreparable effects such as growth impairment, spontan...
متن کاملFetal RHD Genotyping Using Real-Time Polymerase Chain Reaction Analysis of Cell-Free Fetal DNA in Pregnancy of RhD Negative Women in South of Iran
Objective Maternal-fetal RhD antigen incompatibility causes approximately 50% of clinically significant alloimmunization cases. The routine use of prophylactic anti-D immunoglobulin has dramatically reduced hemolytic disease of the fetus and newborn. Recently, fetal RHD genotyping in RhD negative pregnant women has been suggested for appropriate use of anti-D immunoglobulin antenatal prophylaxi...
متن کاملEvaluation of cell-free fetal DNA as a second-trimester maternal serum marker of Down syndrome pregnancy.
BACKGROUND Second-trimester cell-free fetal DNA (studied only in pregnancies with male fetuses) is higher in maternal serum samples from women carrying Down syndrome fetuses than in unaffected pregnancies. In this study we evaluated the potential performance of fetal DNA as a screening marker for Down syndrome. METHODS Data on maternal serum fetal DNA concentrations and the corresponding conc...
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ژورنال
عنوان ژورنال: Indian Journal of Clinical Biochemistry
سال: 2017
ISSN: 0970-1915,0974-0422
DOI: 10.1007/s12291-017-0672-3