منابع مشابه
Cardiac Stem Cell Therapy for Cardiac Repair
OPINION STATEMENT The discovery of adult cardiac stem cells (CSCs) and their potential to restore functional cardiac tissue has fueled unprecedented interest in recent years. Indeed, stem-cell-based therapies have the potential to transform the treatment and prognosis of heart failure, for they have the potential to eliminate the underlying cause of the disease by reconstituting the damaged hea...
متن کاملTherapeutic angiogenesis promotes efficacy of human umbilical cord matrix stem cell transplantation in cardiac repair
Objective(s):Although previous studies have confirmed the beneficial effects of human umbilical cord matrix stem cell (hUCM) transplantation post myocardial infarction (MI), but this stem cell resource has no potential to induce angiogenesis. In order to achieve the process of angiogenesis and cardiomyocyte regeneration, two required factors for cardiac repair agents were examined namely; hUCM ...
متن کاملCell transplantation for cardiac repair.
Despite remarkable progress in contemporary cardiovascular therapy, treatment of heart failure still remains a therapeutic challenge. Pharmacological treatment using -blockers, angiotensin converting enzyme inhibitors, and angiotensin-II receptor blockers, as well as surgical revascularization together with left ventricular reshaping procedures, has improved the quality of life for heart failur...
متن کاملCell therapy for cardiac repair.
Heart failure is a leading cause of morbidity and mortality worldwide. The current strategies for treatment are limited and new therapeutic approaches are needed. This review describes research performed in animal models of cardiac disease and clinical trials and discusses the mechanisms involved in possible beneficial effects of cell therapy. Cell therapy is a promising strategy to treat heart...
متن کاملStem cell differentiation: cardiac repair.
Cellular transplantation has been employed for several years to deliver donor cardiomyocytes to normal and injured hearts. Recent reports of a variety of stem cells with apparent cardiomyogenic potential have raised the possibility of cell transplantation-based therapeutic interventions for heart disease. Here we review the preclinical studies demonstrating that intracardiac transplantation of ...
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ژورنال
عنوان ژورنال: Circulation
سال: 2005
ISSN: 0009-7322,1524-4539
DOI: 10.1161/circulationaha.105.546218