Cefepime-induced neurotoxicity: a systematic review
نویسندگان
چکیده
منابع مشابه
Characterizing Cefepime Neurotoxicity: A Systematic Review
Neurotoxicity due to cefepime has not been well characterized. We performed a systematic review of the literature and included 5 additional cases from our center. Of the 198 cases found, the mean age was 67 years and 87% of patients had renal dysfunction. The most common clinical features were diminished level of consciousness (80%), disorientation/agitation (47%), and myoclonus (40%). It is wo...
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We present here a case of 58-year-old male operated for coronary artery bypass graft surgery with four grafts. He developed neurologic symptoms with injection cefepime which recovered after withdrawal of the drug.
متن کاملCefepime induced neurotoxicity: A case series and review of the literature
Cefepime is a fourth generation cephalosporin which is bactericidal for broad spectrum of organisms. This is a case-series of three patients who presented to our hospital with confusion secondary to cefepime use to treat urinary tract infection (UTI) and health care associated pneumonia (HCAP), after excluding other common etiologies of altered mental status (AMS). Of these three patients, one ...
متن کاملFluoroquinolone Induced Neurotoxicity: A Review
Introduction: Fluoroquinolones (FQs) are commonly used antibiotics both in inpatient and outpatient settings. Their therapeutic use ranges from the common respiratory, urinary tract and gastrointestinal infections to management of drug resistant tuberculosis and febrile neutropenia in immunocompromised patients. [1] Significant features of this group of antibiotics include their wide antibacter...
متن کاملCefepime Neurotoxicity in Patients with Renal Insufficiency
Cefepime is a fourth-generation cephalosporin that is active against both gram-positive and gram-negative organisms. It is administered parenterally for the treatment of severe infections. Approximately 85% of the drug is excreted unchanged by the kidneys. Neurotoxicity in patients with renal failure who are treated with cefepime has been reported sporadically. We report on two senile patients ...
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ژورنال
عنوان ژورنال: Critical Care
سال: 2017
ISSN: 1364-8535
DOI: 10.1186/s13054-017-1856-1