CD4+CD25+ T cells as immunoregulatory T cells in vitro

CD4+CD25+ Immunoregulatory T Cells

CD4(+)CD25(+) immunoregulatory T cells play a pivotal role in preventing organ-specific autoimmune diseases and in tolerance induction to allogeneic organ transplants. We investigated whether these cells could also control graft-versus-host disease (GVHD), the main complication after allogeneic hematopoietic stem cell transplantation (HSCT). Here, we show that the few CD4(+)CD25(+) T cells natu...

T Helper Cells Profile and CD4+CD25+Foxp3+Regulatory T Cells in Polycystic Ovary Syndrome

Background: Polycystic ovary syndrome (PCOS) is considered as the most common cause of female infertility that affects 4-10% of women in the reproductive age. Previous studies have shown the role of a balanced immune response in a successful pregnancy and fertility. Objective: To investigate the T helper cells type 1 (Th1) /Th2/Th17/Treg paradigms in peripheral blood of infertile PCOS compared ...

CD4CD25 Regulatory T Cells Preventing Detrimental Autoimmune Reactions

Objective: Autoimmune diseases will occur when the immune response inflicts damage to tissues in the body. Attempts to overcome this disease have a lot to do but they have not yielded satisfying results. In this study, the function of CD4CD25 regulatory T cells was evaluated for therapeutic potential to prevent the development of autoreactive T

Regulatory T Cells in Colorectal Cancer

One of the essential protection mechanisms of immune system is Treg cells which play an important role in maintenance ofimmune homeostasis. However, they may also inhibit immune functions against tumor cells. It has been reported that Treg cellsare increased in patients suffering from different types of cancer. Increased number of Treg cells has been shown in tumor lymphnodes, peripheral blood,...

Immunoregulatory T Cells Is Antigen Nonspecific