Caution should be taken when using electronic health record database

Caution should be taken in using CD31 for distinguishing the vasculature of lymph nodes.

CORRESPONDENCE An early lesion of pulmonary carcinosarcoma: possible diagnostic problem in frozen section interpretation Sarcomatoid carcinoma is a rare malignant neoplasm of the lung. 1 Its definition was ambiguous until the recent establishment of World Health Organisation (WHO) criteria, according to which it is classified into carcinosarcoma, pleomorphic carcinoma, and spindle cell carcinom...

Vancomycin Safety Monitoring Using an Electronic Health Record Database

An electronic health record-enabled obesity database

BACKGROUND The effectiveness of weight loss therapies is commonly measured using body mass index and other obesity-related variables. Although these data are often stored in electronic health records (EHRs) and potentially very accessible, few studies on obesity and weight loss have used data derived from EHRs. We developed processes for obtaining data from the EHR in order to construct a datab...

Should valproate be taken during pregnancy?

The Australian Registry of Antiepileptic Drug Use in Pregnancy includes 172 instances in which women took sodium valproate, with or without other antiepileptic drugs, during pregnancy. These pregnancies resulted in a substantially higher (p < 0.05) rate of malformed offspring (15.1%) compared with 348 pregnant women who took antiepileptic drugs other than valproate (2.3%) and 40 pregnancies in ...

Why voxel-based morphometric analysis should be used with great caution when characterizing group differences.

A variety of voxel-based morphometric analysis methods have been adopted by the neuroimaging community in the recent years. In this commentary we describe why voxel-based statistics, which are commonly used to construct statistical parametric maps, are very limited in characterizing morphological differences between groups, and why the effectiveness of voxel-based statistics is significantly bi...