Causal Measures for Prognostic and Predictive Biomarkers

نویسندگان

چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Update on prognostic and predictive biomarkers for pancreatic neuroendocrine tumors.

Neuroendocrine tumors (NETs) describe a heterogeneous group of tumors with a wide range of morphologic, functional, and behavioral characteristics. These tumors are often indolent but they have the potential to cause symptoms through release of hormones and through local or distant spread. Pancreatic neuroendocrine tumors (pNET) represent a subset of NETs and they have a unique pattern of sympt...

متن کامل

Prognostic and predictive biomarkers in metastatic castration-resistant prostate cancer.

AJA Biomarkers are any manifestation of a biological process, particularly in patients, that can be measured quantitatively. They can reflect either normal (physiologic) or disease (pathophysiologic) processes. Biomarkers are used in various contexts in prostate cancer. Prognostic biomarkers are related to the natural history of a disease over time, whereas predictive biomarkers are linked to t...

متن کامل

Prognostic and predictive biomarkers in gastroenteropancreatic neuroendocrine tumors.

Neuroendocrine tumors (NET) are a diverse group of tumors that derive from epithelial cells with neuroendocrine differentiation. Gastroenteropancreatic NETs are a subset of NET that arise from the gastrointestinal tract. The natural history and prognosis varies widely between different gastroenteropancreatic NETs, highlighting the importance of identifying accurate prognostic and predictive bio...

متن کامل

Disentangling Prognostic and Predictive Biomarkers Through Mutual Information.

We study information theoretic methods for ranking biomarkers. In clinical trials, there are two, closely related, types of biomarkers: predictive and prognostic, and disentangling them is a key challenge. Our first step is to phrase biomarker ranking in terms of optimizing an information theoretic quantity. This formalization of the problem will enable us to derive rankings of predictive/progn...

متن کامل

Prognostic and Predictive Clinical, Pathological and Molecular Markers for Oral Squamous Cell Carcinoma: review of articles

Approximately 90% of all head and neck malignancies and 94% of oral malignancies are squamous cell carcinoma (SCC). Tobacco smoking is considered as the most important causative agent for SCC. Despite aggressive and multidisciplinary treatment approaches, there has been no significant improvement in 5-year survival over the past 20 years. Several prognostic and predictive clinical, pathological...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Open Journal of Statistics

سال: 2018

ISSN: 2161-718X,2161-7198

DOI: 10.4236/ojs.2018.82014