Caudate nucleus and relearning of delayed alternations in cats

Dissociative effects of selective lesions in the caudate nucleus of cats and rats.

Lesions in the neostriatal region connected to the prefrontal cortex severely impaired delayed alternation in both cats and rats, whereas no such effect was found after damage to other neostriatal regions. These results indicate that the processes mediating delayed alternation are well localized in the neostriatum of both cats and rats. Two possible models of neostriatal functioning are discuss...

Participation of caudate nucleus in different forms of voluntary activity in cats.

Different forms of behavior (instrumental conditioned reflexes, generalization tests, extrapolatory reflexes) were investigated before and after lesions of the caudate nucleus or pharmacological influence on its cholinergic systems. Postoperative deficit was small in well-elaborated forms of behavior and large in complex tasks. Chemical stimulation of the caudate nucleus was followed by depress...

Visual response characteristics of neuronal clusters in the caudate nucleus of behaving cats

Visual response characteristics of neuronal clusters in the caudate nucleus of behaving cats

Background: Anesthetized, paralyzed domestic cats are often used as model organisms in visual neu-rophysiology. However, in the last few decades, behaving animal models have gathered ground inneurophysiology, due to their advantages over anesthetized, paralyzed models.New Method: In the present study a new, behaving, awake feline model is described, which is suitable forchronic ...

Activity of Caudate Nucleus Neurons in a Visual Fixation Paradigm in Behaving Cats

Beside its motor functions, the caudate nucleus (CN), the main input structure of the basal ganglia, is also sensitive to various sensory modalities. The goal of the present study was to investigate the effects of visual stimulation on the CN by using a behaving, head-restrained, eye movement-controlled feline model developed recently for this purpose. Extracellular multielectrode recordings we...