منابع مشابه
Cation Exchange in Mammalian Erythrocytes
Freshly drawn heparinized human whole blood is exposed to x-rays in amounts up to 54,000 r in vitro and then equilibrated under a controlled atmosphere at 24 or 38 degrees C. For as long as 26 hours following exposure, potassium is progressively lost from the cells and quantitatively replaced by sodium with little, if any, osmotic disturbance. The mean rate of loss at 20,000 r and 24 degrees C....
متن کاملCation Exchange between Cells and Plasma of Mammalian Blood
The exchange of potassium between cells and plasma of heparinized human blood has been studied in vitro using the radioactive isotope K(42). The changes in cell and plasma specific activity are characteristic of a simple two-compartment system. The mean of seven determinations of the exchange rate at 38 degrees C. is 1.8 per cent of the cellular potassium per hour. The results indicate that at ...
متن کاملThe monovalent cation "leak" transport in human erythrocytes: an electroneutral exchange process.
The mechanism of the "ground permeability" of the human erythrocyte membrane for K+ and Na+ was investigated with respect to a possible involvement of a previously unidentified specific transport pathway, because earlier studies showed that it cannot be explained on the basis of simple electrodiffusion. In particular, we analyzed and described the increase in the (ouabain+bumetanide+EGTA)-insen...
متن کاملThe mammalian TRPC cation channels.
Transient Receptor Potential-Canonical (TRPC) channels are mammalian homologs of Transient Receptor Potential (TRP), a Ca(2+)-permeable channel involved in the phospholipase C-regulated photoreceptor activation mechanism in Drosophila. The seven mammalian TRPCs constitute a family of channels which have been proposed to function as store-operated as well as second messenger-operated channels in...
متن کاملCarboxylic cation exchange resin effects in dogs.
Reports describing trials of exchange resins in removing cations from the gastrointestinal tract of experimental animals have been limited to toxicity studies and to measurements of the relative magnitudes of the oral intake and the stool output (1-3). In the experiments presented in this paper changes in serum, urine, and stool components, as well as the external and internal balances of certa...
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ژورنال
عنوان ژورنال: Journal of General Physiology
سال: 1951
ISSN: 1540-7748,0022-1295
DOI: 10.1085/jgp.34.5.691