منابع مشابه
Pharmacological Activities of Catharanthus Roseus: a Perspective Review
India possess a rich biodiversity of the medicinal plants that were still not explored completely. The need for the novel pharmaceutical products out from the plant has attained a great interest in the present research world due to the cost and the higher side effects that are associated with the chemically manufactured drugs. Catharanthus roseus,which is a potent medicinal plant many of the ph...
متن کاملThe seco-iridoid pathway from Catharanthus roseus
The (seco)iridoids and their derivatives, the monoterpenoid indole alkaloids (MIAs), form two large families of plant-derived bioactive compounds with a wide spectrum of high-value pharmacological and insect-repellent activities. Vinblastine and vincristine, MIAs used as anticancer drugs, are produced by Catharanthus roseus in extremely low levels, leading to high market prices and poor availab...
متن کامل5-Methyltryptophan resistant cells of Catharanthus roseus.
Several cell lines resistant to 5-methyltryptophan were selected from wild type cells of different Catharanthus roseus suspension cultures. The resistant cells had up to 30 times the normal levels of free tryptophan. Despite the increased pool size of tryptophan anthranilate synthetase activity of resistant cells was as sensitive to inhibition by L-tryptophan as wild type cells. The overproduct...
متن کاملCryopreservation of Alkaloid-Producing Cell Cultures of Periwinkle (Catharanthus roseus).
A procedure for cryogenic storage of alkaloid producing cell lines of periwinkle, Catharanthus roseus (L.) G. Don., has been developed. The procedure differs from established cryopreservation protocols in several aspects. Specifically, 4-day-old suspension subcultures of three cell lines were precultured in nutrient media supplemented with 1 molar sorbitol for 6 to 20 hours. The cells were then...
متن کاملAdenine Phosphoribosyltransferase Activity in Mitochondria o f Catharanthus roseus Cells
Catharanthus roseus (= Vinca rosea), Adenine Phosphori bosyltransferase, Subcellular D istribution, Mitochondria, Purine Salvage Subcellular localization of adenine phosphoribosyltrans ferase was examined in Catharanthus roseus cells. At least 13% of the activity was observed in the particulate fraction with the rest observed in the cytosol. Both differential and Percoll density gradient cent...
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ژورنال
عنوان ژورنال: Acta Scientific Pharmaceutical Sciences
سال: 2019
ISSN: 2581-5423
DOI: 10.31080/asps.2019.03.0393