Cases of meningococcal disease associated with camping site in Spain

Secondary cases of meningococcal disease.

Optimizing strategies for meningococcal C disease vaccination in Valencia (Spain)

BACKGROUND Meningococcal C (MenC) conjugate vaccines have controlled invasive diseases associated with this serogroup in countries where they are included in National Immunization Programs and also in an extensive catch-up program involving subjects up to 20 years of age. Catch-up was important, not only because it prevented disease in adolescents and young adults at risk, but also because it d...

Meningococcal disease: identifying high-risk cases

In the previous issue of Critical Care, Vermont and colleagues presented a simple but well-executed observational study describing the levels of chemokines in the serum of 58 children with meningococcal sepsis. The chemokine levels correlated with disease severity and outcome. Significant correlations were demonstrated between admission chemokine levels and the Paediatric Risk of Mortality scor...

Does eradication of meningococcal carriage in household contacts prevent secondary cases of meningococcal disease?

Comment Strains of meningococci carried in the general population usually belong to non-virulent serological groups and types, even during an epidemic, and hence the ratio of attacks to carriers is low3; in Denmark in 1987 it was 1:17000 (297 cases in a population of 5-1 million). If the secondary attack rate among household contacts of an index case of meningococcal disease is 500-800 times th...

Neonatal meningococcal conjunctivitis associated with meningococcal meningitis.

Two infants are described in whom identical strains of meningococcus were isolated from both the eyes and the cerebrospinal fluid. This suggests that the eye may be a portal of entry in at least some cases of perinatally acquired neonatal meningococcal disease and has important implications for the management of purulent conjunctivitis in the newborn.