منابع مشابه
Cardiovascular Toxicity of Local Anesthetics
In general, much greater doses of local anesthetics are required to produce cardiovascular (CV) toxicity than CNS toxicity. Similar to CNS toxicity, potency for CV toxicity reflects the anesthetic potency of the agent. Recent attention has focused on the apparently exceptional cardiotoxicity of the more potent, more lipid-soluble agents (bupivacaine, levo-bupivacaine, etidocaine, ropivacaine). ...
متن کامل[Neuroprotective effects of anesthetics].
During cerebral ischaemia, energetic failure of injured cells together with excessive release of glutamate the most common excitatory amino acid in the brain, lead to excitotoxicity and immediate or delayed neuronal death. There is strong experimental evidence to support the neuroprotective role played by anaesthetic agents. Hence, barbiturates, volatile anesthetics or ketamine exhibit signific...
متن کاملEffects of anesthetics
The aim of this study was to compare the systemic hemodynamic effects of four commonly used anesthetic regimens in mice chronically instrumented for direct and continuous measurements of cardiac output (CO). Mice (CD-1, Swiss and C57Bl6) were instrumented with a transit-time flow probe placed around the ascending aorta for measurement of CO. An arterial catheter was inserted four to five days l...
متن کاملLocal Anesthetics in Patients with Cardiovascular Diseases
A significant problem in the dental medicine is pain alleviation. Many studies in the dental anesthesiology result in the production of new agents for locoregional anesthesia. Objective: This article aim to present the results of the last studies on the effect of the local anesthetics used in the oral surgery on patients with cardiovascular diseases. Material: A general review of the existing l...
متن کاملCardiovascular toxicity of local anesthetics: an alternative hypothesis.
The current study examined the possibility that high local anesthetic concentrations within the central nervous system could contribute to the toxic cardiovascular effects observed clinically after an accidental intravenous injection. Equal numbers of molecules of lidocaine (1.6 microliter of a 2% solution) and bupivacaine (1.0 microliter of a 4% solution) were injected at three vasomotor and c...
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ژورنال
عنوان ژورنال: The Japanese Journal of Veterinary Anesthesiology
سال: 1983
ISSN: 0285-2209,2185-2987
DOI: 10.2327/jvas1970.14.1