Cardiovascular and neuropsychiatric risks of varenicline
نویسندگان
چکیده
منابع مشابه
Cardiovascular and neuropsychiatric risks of varenicline: a retrospective cohort study
BACKGROUND Varenicline is an effective pharmacotherapy to aid smoking cessation. However, its use is limited by continuing concerns about possible associated risks of serious adverse cardiovascular and neuropsychiatric events. The aim of this study was to investigate whether use of varenicline is associated with such events. METHODS In this retrospective cohort study, we used data from patien...
متن کاملCardiovascular and neuropsychiatric risks of varenicline and bupropion in smokers with chronic obstructive pulmonary disease.
BACKGROUND Varenicline and bupropion are effective smoking cessation treatments, but there are concerns about their safety in smokers with COPD. OBJECTIVE To investigate whether varenicline and bupropion are associated with serious adverse cardiovascular and neuropsychiatric events in smokers with COPD. METHODS In a retrospective cohort study, we used data from 14 350 patients with COPD inc...
متن کاملVarenicline, smoking cessation, and neuropsychiatric adverse events.
OBJECTIVE In 2009, the U.S. Food and Drug Administration issued a black box warning for varenicline regarding neuropsychiatric events. The authors used data from randomized controlled trials and from a large Department of Defense (DOD) observational study to assess the efficacy and safety of varenicline. METHOD The authors reanalyzed data from the 17 placebo-controlled randomized controlled t...
متن کاملComparison of Cardiovascular Risks following Smoking Cessation Treatments Using Varenicline vs. NRT among Schizophrenic Smokers
Methods: A population-based retrospective cohort study was conducted using the General Electric (GE) electronic medical record database (1995-2011). The cohort consisted of patients with a diagnosis of schizophrenia or schizoaffective disorder (ICD-9 code 295.00-295.99) and who had newly initiated use of any smoking cessation medication. We excluded our cohort who (1) were not prescribed atypic...
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ژورنال
عنوان ژورنال: The Lancet Respiratory Medicine
سال: 2016
ISSN: 2213-2600
DOI: 10.1016/s2213-2600(15)00523-8