Cardiac transplantation in adult congenital heart disease: a narrative review

Congenital Heart Disease Sudden Cardiac Death in Adult Congenital Heart Disease

Background—Sudden cardiac death (SCD) is a major cause of mortality in adults with congenital heart disease (CHD). The aim of this study was to determine the adult CHD population at risk of SCD and the clinical parameters associated with SCD. Methods and Results—We performed a multicenter case-control study. Patients who died suddenly as a result of proven or presumed arrhythmia were included (...

CONGENITAL HEART DISEASE Changing practice of cardiac surgery in adult patients with congenital heart disease

Objectives: To review 13 years’ data from a unit for grown ups with congenital heart disease (GUCH) to understand the change in surgical practice. Methods: Records were reviewed of patients over 16 years of age undergoing surgery between 1 January 1990 and 31 December 2002 in a dedicated GUCH unit. Patients with atrial septal defects were included but not those with Marfan’s syndrome or undergo...

Sudden Cardiac Death in Adult Congenital Heart Disease.

Sudden death of presumed arrhythmic etiology is a leading cause of mortality in adults with congenital heart disease. Anticipated benefits of the implantable cardioverter-defibrillator (ICD) must be weighed against high complication rates. Without robust evidence from randomized trials, caregivers face difficult decisions in selecting appropriate candidates. Although secondary prevention indica...

Adult Congenital Heart Disease

Heart Transplantation in Congenital Heart Disease

Orthotopic heart transplantation has been performed in pediatric patients for 27 years. Indications changed through the years, showing the increase of patients receiving a heart transplant for congenital heart defects, after having experienced repeated surgical palliations. At present, 1-year survival > 65% can be expected following pediatric heart transplantation. Morbidity other than hyperten...