Cardiac parasympathetic hyperresponsiveness in spontaneously hypertensive rats.
نویسندگان
چکیده
منابع مشابه
Cardiac parasympathetic hyperresponsiveness in spontaneously hypertensive rats.
The bradycardic response to baroreceptor stimulation is impaired in human and experimental hypertension. Because this bradycardia mainly depends on the vagus, this may reflect a reduced cardiac parasympathetic responsiveness, which would parallel the reduced cardiac adrenergic responsiveness observed in hypertension. To test this hypothesis, 12-week-old spontaneously hypertensive rats (n = 12) ...
متن کاملCardiac hypertrophy in spontaneously hypertensive rats.
The energy metabolism of cardiac hypertrophy in spontaneously hypertensive rats (SHR) was studied chronologically by histochemical and in part chemical methods. The activities of various enzymes, such as glucose-6-phosphate dehydrogenase (G6PDH), lactate dehydrogenase (LDH), isocitrate dehydrogenase, succinate dehydrogenase, beta-hydroxybutylate dehydrogenase (beta-HBDH) and monoamine oxidase (...
متن کاملCardiac contractile reserve in spontaneously hypertensive rats.
1. In response to graded infusions of isoprenaline, adult spontaneously hypertensive rats (20-24 weeks old) showed diminished responses of left ventricular contractile indices, diminished chronotropic responses and impairment of left ventricular relaxation rate as compared with matched Kyoto-Wistar rats. 2. These findings suggest reduced capacity to increase contractility in response to stress.
متن کاملCardiac tolerance to ischemia in neonatal spontaneously hypertensive rats.
Hypertension is the risk factor of serious cardiovascular diseases, such as ischemic heart disease and atherosclerosis. The aim of the present study was to analyze the development of cardiac tolerance to ischemia in neonatal spontaneously hypertensive rats (SHR) and possible protective effect of ischemic preconditioning (IP) or adaptation to intermittent high-altitude hypoxia (IHAH). For this p...
متن کاملCardiac output in conscious and almost unrestrained spontaneously hypertensive rats.
Cardiac output and arterial pressure in the conscious state were measured in spontaneously hypertensive rats and normal control rats with chronically implanted electromagnetic flow probe and arterial indwelling cannula. Cardiac index at rest was greater in hypertensive rats than in controls. However, the mean arterial pressure in probe implanted hypertensive rats was significantly lower than th...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Hypertension
سال: 1992
ISSN: 0194-911X,1524-4563
DOI: 10.1161/01.hyp.19.6.653