منابع مشابه
Phenylalanine Metabolism: Phenylketonuria
The hydroxylase is a trimer of approximately 150 kDa of identical subunits and is located predominantly in the liver. The enzyme has been mapped to human chromosome 12q22-24.1, where the gene comprises 13 exons extending over 90 kb of genomic DNA. Deletions in the gene are not common. A frequent cause among northern Europeans (~40%) is a G-to-A transition at the 5′ donor splice site in intron 1...
متن کاملThe effect of maternal hypothyroidism during pregnancy on carbohydrate metabolism in adulthood in rats
Introduction: Many of the diseases of adulthood are originated from the intrauterine conditions during fetal life. Because of the importance of thyroid hormones in growth and development of the fetus, the effects of maternal hypothyroidism on carbohydrate metabolism in adulthood was investigated. Methods: Pregnant rats were divided into the fetal hypothyroidism (FH) and the control (C) group...
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Fenfluramine, an anorexigenic agent, is widely used in the treatment of obesity. Besides its anorectic effect, it may also have some effects on general metabolism with the consequence of weight loss. In this study, the effect of fenfluramine on the concentrations of some parameters related to carbohydrate metabolism was investigated. It was shown that the serum insulin level was reduced by ...
متن کاملCarbohydrate Metabolism
G lucose is central to all of metabolism. It is the universal fuel for human cells and the source of carbon for the synthesis of most other compounds. Every human cell type uses glucose to obtain energy. The release of insulin and glucagon by the pancreas aids in the body’s use and storage of glucose. Other dietary sugars (mainly fructose and galactose) are converted to glucose or to intermedia...
متن کاملCarbohydrate Metabolism in Leukocytes
In normal polymorphonuclear leukocytes the occurrence of a high rate of aerobic glycolysis with a concomitant large formation of lactic acid has been demonstrated (1, 2) and the enzymes and intermediates of the Embden-Meyerhof pathway have been isolated and identified (3-5). There are indications for the presence and activity of the Krebs cycle, but the contribution of this cycle to metabolism ...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1980
ISSN: 0031-3998
DOI: 10.1203/00006450-198014070-00001