Carbamazepine-induced hyponatremia

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[Carbamazepine-induced hyponatremia].

Treatment with some drugs may lead to the syndrome of inappropriate antidiuretic hormone secretion (SIADH), the presence of which is more likely in some populations, including people who are elderly or who take diuretics. Resulting drug-induced hyponatremia is often mild and usually resolves following water restriction and withdrawal of the drug. In some patients, however, it may be a potential...

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Severe hyponatremia in a patient treated with levomepromazine and carbamazepine.

A 40-year-old man was brought to hospital because of grand mal seizures in July, 2000. Seven hours before admission, he vomited once and drank approximately 6 liters of water within two hours because of throat discomfort. Thirty minutes later, he suffered six grand mal seizures. His medical history included cerebral palsy at the age of one year complicated with mental retardation and absence ep...

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Incidence and Predictive Factors of Hyponatremia in Acute Carbamazepine Exposure

Introduction: Hyponatremia, an electrolyte abnormality reported during long-term treatment with carbamazepine (CBZ), is increasingly observed in acute poisoning. Its incidence and predictive factors varies from one study to anotherbecause of heterogeneity of studied patients and inclusion criteria. Objective: We aimed to study the incidence of hyponatremia in CBZ poisoning in our specialized to...

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Thiazide-Induced Hyponatremia

The importance of thiazide-induced hyponatremia (TIH) is reemerging because thiazide diuretic prescription seems to be increasing after the guidelines recommending thiazides as first-line treatment of essential hypertension have been introduced. Thiazide diuretics act by inhibiting reabsorption of Na(+) and Cl(-) from the distal convoluted tubule by blocking the thiazide-sensitive Na(+)/Cl(-) c...

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ژورنال

عنوان ژورنال: British Journal of Anaesthesia

سال: 2016

ISSN: 0007-0912

DOI: 10.1093/bja/el_13266