منابع مشابه
Mechanism of action of organophosphorus and carbamate insecticides.
Organophosphorus and carbamate insecticides are toxic to insects and mammals by virtue of their ability to inactivate the enzyme acetylcholinesterase. This review addresses the mechanism of inhibition of acetylcholinesterase by organophosphorus and carbamate esters, focusing on structural requirements necessary for anticholinesterase activity. The inhibition of acetylcholinesterase by these com...
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Background: Leishmaniosis is a prevalent tropical parasitic disease, which is caused by Leishmania protozoa. The infection can be limited in immune-competent individuals; however, in immune-compromised individuals it could proceed to chronic and ulcerative disease. The reservoirs are carnivores, and rodents and its vectors are Phlebotomus and Lutzumia. Methods: The prevalence of different spice...
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Malaria (vector: Anopheles gambiae) is a major infectious disease that kills about 1 million people each year. For the improvement of its treatment and vector control during the past decades, several issues such as high medicine cost, insecticide resistance, and lack of an effective vaccine have prevented adequate control of malaria. Additionally, the low selectivity of malaria vector insectici...
متن کاملDose-additive inhibition of chinook salmon acetylcholinesterase activity by mixtures of organophosphate and carbamate insecticides.
Organophosphate and carbamate insecticides are widely detected in surface waters of the western United States. These chemicals interfere with acetylcholine-mediated synaptic transmission in the nervous systems of fish and other aquatic animals via the inhibition of AChE (acetylcholinesterase) enzyme activity. Anticholinesterase insecticides commonly co-occur in the environment. This raises the ...
متن کاملProbabilistic assessment of the cumulative acute exposure to organophosphorus and carbamate insecticides in the Brazilian diet.
In the present study, the cumulative exposure of 25 acetylcholinesterase (AChE) inhibiting pesticides through the consumption of nine fruits and vegetables by the Brazilian population was assessed. Food consumption data were obtained from a household budget survey conducted in all Brazilian states from July 2002 to June 2003. Residue data from 4001 samples were obtained from the Brazilian natio...
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ژورنال
عنوان ژورنال: Journal of Synthetic Organic Chemistry, Japan
سال: 1971
ISSN: 0037-9980,1883-6526
DOI: 10.5059/yukigoseikyokaishi.29.254