Capsaicin induces degeneration of cutaneous autonomic nerve fibers

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Capsaicin induces degeneration of cutaneous autonomic nerve fibers.

OBJECTIVE To determine the effects of topical application of capsaicin on cutaneous autonomic nerves. METHODS Thirty-two healthy subjects underwent occlusive application of 0.1% capsaicin cream (or placebo) for 48 hours. Subjects were followed for 6 months with serial assessments of sudomotor, vasomotor, pilomotor, and sensory function with simultaneous assessment of innervation through skin ...

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ژورنال

عنوان ژورنال: Annals of Neurology

سال: 2010

ISSN: 0364-5134

DOI: 10.1002/ana.22126