Capillary Tube Technique for Serologic Screening of Syphilis
نویسندگان
چکیده
منابع مشابه
Novel Treponema pallidum serologic tests: a paradigm shift in syphilis screening for the 21st century.
The mainstay of diagnosis for Treponema pallidum infections is based on nontreponemal and treponemal serologic tests. Many new diagnostic methods for syphilis have been developed, using specific treponemal antigens and novel formats, including rapid point-of-care tests, enzyme immunoassays, and chemiluminescence assays. Although most of these newer tests are not yet cleared for use in the Unite...
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A surface immunofluorescence assay (SIFA) using live spirochetes was analyzed and compared with Western blot (WB), fluorescent treponemal antibody absorption (FTA-ABS), microhemagglutination (MHA-TP), and Treponema pallidum immobilization (TPI) assays for detecting serum antibodies to T. pallidum in patients with syphilis, in disease controls, and in healthy subjects. SIFA and WB were 99% sensi...
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The effects of temperature on the results obtained in the older serological tests for syphilis employing lipoidal antigens is well known. In fact, the differences in test results obtained when certain tests were performed at different temperatures served not only as the basis for attempted differentiation of syphilitic from so-called biologic false positive reactions (Kahn, 1940), but also for ...
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Serologic monitoring is the way to determine adequate treatment response, which is typically defined as a fourfold decline in Rapid Plasma Reagin (RPR) or Veneral Disease Research Laboratory (VDRL) titer within 6 months of treatment for patients with primary or secondary syphilis and within 12 months of treatment for patients with early latent syphilis. Studies documented close to 100% rate ser...
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ژورنال
عنوان ژورنال: Public Health Reports (1896-1970)
سال: 1953
ISSN: 0094-6214
DOI: 10.2307/4588413