Canonical Correlation Analysis for Gene-Based Pleiotropy Discovery
نویسندگان
چکیده
منابع مشابه
Canonical Correlation Analysis for Gene-Based Pleiotropy Discovery
Genome-wide association studies have identified a wealth of genetic variants involved in complex traits and multifactorial diseases. There is now considerable interest in testing variants for association with multiple phenotypes (pleiotropy) and for testing multiple variants for association with a single phenotype (gene-based association tests). Such approaches can increase statistical power by...
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ژورنال
عنوان ژورنال: PLoS Computational Biology
سال: 2014
ISSN: 1553-7358
DOI: 10.1371/journal.pcbi.1003876