Canine transmissible venereal tumour: Cytogenetic origin, immunophenotype, and immunobiology. A review

Pathogenesis and evolution o f Canine Transmissible Venereal Tumour

Canine Transmissible Venereal Tumour (CTVT) is a neoplastic disease occurring naturally in dogs. CTVT is usually sexually transmitted, but transmission may occur by licking, biting, or scratching tumour-affected areas. Cytogenetic studies directed to verify the cell transmissibility of the CTVT showed that the tumour cells are characterized by a rearranged karyotype, which is similar in tumours...

Transmissible Venereal Tumour in Dogs

Cytomorphological Study of Canine Transmissible Venereal Tumor

Introduction Canine transmissible venereal tumor (CTVT) is classified as a round cell tumor. It always revealed in round to ovoid shaped cell, moderate amount of vacuolated cytoplasm with a large round to ovoid nucleus and prominent nucleoli (2). However, Amaral et al. (2007) reported that CTVT cytomorphology was classified into three types according to the majority of cell type population: pla...

Cytologic subtypes of canine transmissible venereal tumor.

Canine transmissible venereal tumor (CTVT) is a transplantable neoplasm that has stimulated much scientific effort to determine its cell of origin, mode of transmission, and reasons for spontaneous regression as well as similarities with other types of animal and human cancers. In 1994, on the basis of the hypothesis that different cytomorphologic types of CTVT may have different biologic behav...

Evaluation of a genetic assay for canine transmissible venereal tumour diagnosis in Brazil.

The canine transmissible venereal tumour (CTVT) is a transmissible cancer that is spread between dogs by the allogeneic transfer of living cancer cells. The infectious agents in CTVT are the living cancer cells themselves, which are transmitted between dogs during coitus. CTVT first arose several thousand years ago and the disease has a global distribution and is frequently observed in dogs fro...