Canine Corneal Stromal Cells Have Multipotent Mesenchymal Stromal Cell Properties In Vitro

Resistance of Multipotent Mesenchymal Stromal Cells to Anoxia In Vitro

Multipotent Mesenchymal Stromal Cells for Autoimmune Diseases.

SUMMARY: Multipotent mesenchymal stromal cells (MSC) are under consideration for the treatment of autoimmune disease (AD) based on their in vitro antiproliferative properties, efficacy in animal models, apparent low acute toxicity, and the early positive anecdotal outcomes in human acute graft versus host disease. Phase I/II clinical trials are under way in multiple sclerosis and Crohn's diseas...

Mesenchymal Stromal Cells Support Endometriotic Stromal Cells In Vitro

Endometriosis is an inflammatory disease marked by ectopic growth of endometrial cells. Mesenchymal stromal cells (MSC) have immunosuppressive properties that have been suggested as a treatment for inflammatory diseases. Therefore, the aim herein was to examine effects of allogeneic MSC on endometriosis-derived cells in vitro as a potential therapy for endometriosis. MSC from allogeneic adipose...

Multipotent Mesenchymal Stromal Cells: Possible Culprits in Solid Tumors?

The clinical use of bone marrow derived multipotent mesenchymal stromal cells (BM-MSCs) in different settings ranging from tissue engineering to immunotherapies has prompted investigations on the properties of these cells in a variety of other tissues. Particularly the role of MSCs in solid tumors has been the subject of many experimental approaches. While a clear phenotypical distinction of tu...

Immunomodulatory properties of mesenchymal stromal cells Running head: Immunomodulatory properties of mesenchymal stromal cells

Mesenchymal stem cells (MSCs) are multipotential nonhematopoietic progenitor cells capable of differentiating into multiple lineages of the mesenchyme. MSCs have emerged as a promising therapeutic modality for tissue regeneration and repair. Further clinical interest has been raised by the observation that MSCs are immunoprivileged and, more importantly, display immunomodulatory capacities. Alt...