Candesartan ameliorates brain inflammation associated with Alzheimer's disease
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Candesartan Inhibits Carotid Intimal Thickening and Ameliorates Insulin Resistance in
This study investigates the effects of candesartan, an angiotensin II type 1 receptor blockade, on carotid arterial intimal thickening and glucose tolerance in balloon-injured male Wistar fatty rats and their littermates (Wistar lean rats). Candesartan was orally administered to 12-week-old rats for 21 days, and age-matched rats without the agent were used as the respective controls. Balloon ca...
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Recent evidence suggests that higher-than-usual antihypertensive dosages of renin-angiotensin-aldosterone system blockers may provide additional protection from progression of chronic renal disease; however, there have been few long-term studies, and the underlying mechanisms remain uncertain. This study examined the effects of long-term (14 mo) administration of ultrahigh dosages of the angiot...
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ژورنال
عنوان ژورنال: CNS Neuroscience & Therapeutics
سال: 2018
ISSN: 1755-5930
DOI: 10.1111/cns.12802