Cancer Treatment: End-point Evaluation/New Horizons in Oncology
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چکیده
منابع مشابه
ESMO Open—Cancer Horizons and the future of oncology
Correspondence to Professor Christoph C Zielinski; christoph.zielinski@ meduniwien.ac.at In recent years we have witnessed an almost complete repositioning of oncology. Our understanding of the basic biology of the disease has evolved, as has our view of cancers that were once considered as a single entity and are now known to be composed of a wide variety of molecular subgroups. In tandem, the...
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BACKGROUND In cancer clinical trials, the standard end points include response rates, progression free and overall survival, toxicity. These evaluation criteria do not measure how the cancer and its treatment affect the quality of life of cancer patients. DESIGN The relevant literature was reviewed for the purposes of determining when, how and why quality of life should be measured in cancer ...
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s revisited. Ann Intern Med 1990; 113: 69–76.50E V I D E N C E B A S E D O N C O L O G Y End Points and United States Food and Drug Adminis trat ionApproval of Oncology Drugs By John R. Johnson, Grant Williams, and Richard Pazdur Purpose: To summarize the end points used by theUnited States Food and Drug Administration (FDA) to ap-prove new cancer drug applications over the ...
متن کاملNEW HORIZONS Oxidative Stress : A Novel Strategy in Cancer Treatment
From the P. G Deptt. of Pharmacology & Therapeutics, *Obstretics & Gyaneacology, **General Medicine GMC, Jammu (J&K). Correspondece to: Dr. Vishal R Tandon, Senior Demonstrator, PG Department of Pharmacology & Therapeutics, GMC, Jammu (J&K). Introduction There is an equilibrium between a free radical (FR)/ reactive oxygen species (ROS) formation and endogenous antioxidant defense mechanisms, bu...
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ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 1984
ISSN: 0007-0920,1532-1827
DOI: 10.1038/bjc.1984.128