Cancer therapy utilizing an adenoviral vector expressing only E1A
نویسندگان
چکیده
منابع مشابه
Adenoviral E1A function through Myc.
The study of DNA tumor viruses has been invaluable in uncovering the cellular nodes and pathways that contribute to oncogenesis. Perhaps one of the best-studied oncoproteins encoded by a DNA tumor virus is adenovirus E1A, which modifies the function of key regulatory proteins such as retinoblastoma (Rb) and the chromatin remodeling protein p400. Although the interaction of E1A with Rb has long ...
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ژورنال
عنوان ژورنال: Cancer Gene Therapy
سال: 2002
ISSN: 0929-1903,1476-5500
DOI: 10.1038/sj.cgt.7700436