Cancer stem cells in adult gliomas
نویسندگان
چکیده
منابع مشابه
Adult stem cells and cancer.
Rubio et al. (1) reported in Cancer Research that adipose tissue– derived stem cells acquired a transformed phenotype after longterm culture in vitro . This article has been cited together with our article published in the same issue (2) as evidence for the malignant transformation potential of stem cells by the news media. Whereas our study showed the dangers of having a continuous high level ...
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Malignant gliomas, particularly glioblastoma multiforme (GBM) tumors, are very difficult to treat by conventional approaches. Although most of the tumor mass can be removed by surgical resection, radiotherapy, and chemotherapy, it eventually recurs. There is growing evidence that cancer stem cells (CSCs) play an important role in tumor recurrence. These stem cells are radioresistant and chemore...
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The presence of stem cells in leukemia and solid tumors has been demonstrated in recent decades. Cancer stem cells have the potency of tumorigenesis; furthermore, they have the ability of self-renewing and differentiation like other stem cells. They also play important role in the process of tumor invasion and metastasis. Several studies have been performed to discover the spe...
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ژورنال
عنوان ژورنال: Atlas of Genetics and Cytogenetics in Oncology and Haematology
سال: 2012
ISSN: 1768-3262
DOI: 10.4267/2042/46077