Cancer of unknown primary site: 20 questions to be answered

Cancer of unknown primary site.

Copyright © 2014 Massachusetts Medical Society Cancer of unknown primary site is a heterogeneous group of cancers for which the anatomical site of origin remains occult after detailed investigations.1,2 The emergence of sophisticated imaging, immunohistochemical testing, and molecular-profiling tools has influenced our approach to unknown primary cancer, although it has also increased the ambig...

[Metastatic cancer of unknown primary site].

The history, physical examination, radiographic and laboratory studies and histological diagnosis must be completely evaluated to search for the primary tumor. For diagnosis of cervical lymph node metastasis, not only whole body examination but also head and neck examination is important in which quadrascopy (nasopharyngeal, laryngeal and esophageal fiberoscopy and bronchoscopy) must be perform...

Unmarried Mothers: Some Questions to Be Answered and Some Answers to Be Questioned

Can primary care physicians' questions be answered using the medical journal literature?

Medical librarians and informatics professionals believe the medical journal literature can be useful in clinical practice, but evidence suggests that practicing physicians do not share this belief. The authors designed a study to determine whether a random sample of "native" questions asked by primary care practitioners could be answered using the journal literature. Participants included fort...

Hair restoration: answered questions.

Dr. Dzubow's comments in "Hair Restoration: Turbo Transplants and Fractured Follicles" (Dermatol Surg 1995;21:283), regarding Dr. William Rassman's recent article "Micrografting in Extensive Quantities" (Dermatol Surg 1995;21:306-11), state that "questions remain unanswered." I have been working closely with Dr. Rassman for some time and perform extensive micrografting myself. In addition, I ha...