Cancer Clinical Trial Accrual: We Have a Problem
نویسندگان
چکیده
منابع مشابه
Clinical Trial Accrual: Obstacles and Opportunities
Less than 2% of patients diagnosed with cancer participate in a clinical trial in the United States (1). Gynecologic oncology patients do not appear to participate in trials with any more frequently than other cancer types. While gains in progression free survival have continued to improve overall life span for women with advanced gynecologic cancers, more cures have not been realized. Clinical...
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In the November 15, 2010 edition of Clinical Cancer Research, Cheng and colleagues describe an important finding, namely, the association between trial development time and accrual success (1). Their article also reports accrual success rates for NCI Cancer Therapy Evaluation Program (CTEP)-sponsored trials. This publication formally publishes the finding that 40% of cancer clinical trials of a...
متن کاملDesign-phase prediction of potential cancer clinical trial accrual success using a research data mart.
BACKGROUND Many cancer interventional clinical trials are not completed because the required number of eligible patients are not enrolled. OBJECTIVE To assess the value of using a research data mart (RDM) during the design of cancer clinical trials as a predictor of potential patient accrual, so that less trials fail to meet enrollment requirements. MATERIALS AND METHODS The eligibility cri...
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Purpose: This paper reports on the issues involved in improving accruals for cancer-related clinical trials. Clinical trials aim to determine the efficacy of novel therapies and must be conducted before new medical treatments become available to the public. In order for the clinical trial to be successful, a predetermined number of patients with an appropriate set of medical conditions must be ...
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Cancer prevention and control involves a diverse spectrum of activities that range from preventing the disease to providing rehabilitation to its survivors. The range of activities included within the definition of cancer prevention and control makes it difficult to determine factors that would predict accrual to specific cancer prevention and control trials. The participation of 36 CCOP organi...
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ژورنال
عنوان ژورنال: Journal of Cancer Education
سال: 2011
ISSN: 0885-8195,1543-0154
DOI: 10.1007/s13187-011-0224-0