Can immunogenetics illuminate the diverse manifestations of respiratory infections?

Immunogenetics of Small Ruminant Lentiviral Infections

The small ruminant lentiviruses (SRLV) include the caprine arthritis encephalitis virus (CAEV) and the Maedi-Visna virus (MVV). Both of these viruses limit production and can be a major source of economic loss to producers. Little is known about how the immune system recognizes and responds to SRLVs, but due to similarities with the human immunodeficiency virus (HIV), HIV research can shed ligh...

Diverse manifestations of trichloroethylene.

Trichloroethylene, a solvent used in a variety of industrial settings for more than 60 years, has caused adverse health effects on the central and peripheral nervous system, the skin, liver, kidney, and heart. Three men have shown relatively unusual manifestations secondary to exposure to trichloroethylene in degreasing operations in the jewelry industry. Toxic encephalopathy, hepatitis, and ca...

Can Our Experiments Illuminate Reality?

Fungal infections of the Respiratory Tract-Section 1

Fungal infections of the Respiratory Tract are important causes of morbidity and mortality in immunocompromised hospitalized patients. Among these patients are those receiving cytotoxic chemotherapy for neoplastic diseases, those undergoing bone marrow stem cell transplantation or organ transplantation, and those affected with the acquired immune deficiency syndrome. Invasive Aspergillosis has ...

Fungal Infections of Respiratory Tract-Final Section

Histoplasma capsulatum var. capsulatum, Blastomyces dermatitidis, Coccidioides immitis, Paracoccidioides brasiliensis, and Penicillium marneffei are endemic dimorphic fungi that may infect the respiratory tract. Sporothrix schenkeii, which manifests the typical thermal dimorphism of the endemic dimorphic organisms, does not seem to follow a geographically defined endemic pattern of distribution...