Can .GAMMA.-Glutamyltransferase be an Additional Marker of Arterial Stiffness?
نویسندگان
چکیده
منابع مشابه
Canγ-Glutamyltransferase be an Additional Marker of Arterial Stiffness?
used diagnostic test of alcoholic liver disease and has been regarded as a marker of alcohol consumption,1 but recently, it has been suggested than GGT is independently associated with cardiovascular mortality and atherosclerosis. 2–4 One report stated that GGT activity had been detected in atheromatous plaques of carotid and coronary arteries. 5 However, the mechanism by which GGT is associate...
متن کاملThe relationship of gamma-glutamyltransferase to C-reactive protein and arterial stiffness.
BACKGROUND AND AIMS The relationships between gamma-glutamyltransferase (GGT), C-reactive protein (CRP), and arterial stiffness have not been fully investigated. The aim of this study was to clarify whether serum GGT is related to CRP and arterial stiffness estimated using brachial-ankle pulse wave velocity (baPWV). METHODS AND RESULTS The subjects were 3412 males and 854 females. GGT, CRP, b...
متن کاملAssociation of serum gamma-glutamyltransferase with arterial stiffness in established coronary artery disease.
Serum gamma-glutamyltransferase (GGT) has been reported to predict vascular risk. We enrolled 978 patients (507 men and 471 women) with established coronary artery disease (CAD). The GGT, brachial-ankle pulse wave velocity ([baPWV] to assess arterial stiffness), and conventional risk factors were evaluated. The means of baPWV tend to increase in both genders according to GGT tertiles. Body mass...
متن کاملAssociation between γ-glutamyltransferase, adiponectin and arterial stiffness.
AIM Serum γ-glutamyltransferase (GGT) is used as a marker of hepatic dysfunction. Recently, several studies reported that GGT is significantly associated with cardiovascular mortality and atherosclerosis. Adiponectin is known to play an important role in the development of atherosclerosis, but its physiologic role has yet to be fully determined. In this study, we investigated the relationships ...
متن کاملIs serum gamma glutamyltransferase a marker of oxidative stress?
The primary role of cellular gamma glutamyltransferase (GGT) is to metabolize extracellular reduced glutathione (GSH), allowing for precursor amino acids to be assimilated and reutilized for intracellular GSH synthesis. Paradoxically, recent experimental studies indicate that cellular GGT may also be involved in the generation of reactive oxygen species in the presence of iron or other transiti...
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ژورنال
عنوان ژورنال: Circulation Journal
سال: 2007
ISSN: 1346-9843,1347-4820
DOI: 10.1253/circj.71.1715