Calcitonin Screening in Nodular Goiter—Upper Limits

Calcitonin screening and pentagastrin testing: predictive value for the diagnosis of medullary carcinoma in nodular thyroid disease.

CONTEXT Serum calcitonin (hCT) measurement may be useful for detecting medullary thyroid carcinoma (MTC), but the routine use of hCT after pentagastrin stimulation to screen patients with nodular thyroid disease remains controversial. PATIENTS A total of 1007 patients (567 females and 440 males) with nodular thyroid disease and a mean age of 55+/-14 (mean+/-S.D.) years were included in the st...

Routine calcitonin measurement in nodular thyroid disease management: is it worthwhile?

PURPOSE To evaluate the diagnostic accuracy of routine calcitonin measurement in patients with nodular thyroid disease. METHODS Consecutive patients with nodular thyroid disease (n = 640) were studied. Serum calcitonin levels were measured under basal conditions, and when basal values were between 10-100 pg/mL, testing was repeated after pentagastrin (PG) stimulation. Patients with previously...

Calcitonin determination in nodular goitre – diagnostic investigations of medullary thyroid cancer

Limits in modified categories of interest

‎We firstly prove the completeness of the category of crossed modules in a modified category of interest‎. ‎Afterwards‎, ‎we define pullback crossed modules and pullback cat objects that are both obtained by pullback diagrams with extra structures on certain arrows‎. ‎These constructions unify many corresponding results for the cases of groups‎, ‎commutative algebras and can also be adapted to ...

Usefulness of preoperative serum calcitonin in patients with nodular thyroid disease without suspicious history or cytology for medullary thyroid carcinoma.

OBJECTIVE To evaluate the usefulness of preoperative serum calcitonin (sCT) in patients with nodular disease without suspicion of medullary thyroid carcinoma (MTC) in history or cytology. PATIENTS AND METHODS sCT was measured before thyroidectomy in 494 patients with nodular disease who had no family history of MTC or multiple endocrine neoplasia type 2, and no cytological suspicion of MTC. ...