Caenorhabditis elegans OSR-1 Regulates Behavioral and Physiological Responses to Hyperosmotic Environments

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Caenorhabditis elegans OSR-1 regulates behavioral and physiological responses to hyperosmotic environments.

The molecular mechanisms that enable multicellular organisms to sense and modulate their responses to hyperosmotic environments are poorly understood. Here, we employ Caenorhabditis elegans to characterize the response of a multicellular organism to osmotic stress and establish a genetic screen to isolate mutants that are osmotic stress resistant (OSR). In this study, we describe the cloning of...

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Mammalian TRPV4 (VR-OAC) directs behavioral responses to osmotic and mechanical stimuli in Caenorhabditis elegans.

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ژورنال

عنوان ژورنال: Genetics

سال: 2004

ISSN: 1943-2631

DOI: 10.1534/genetics.167.1.161