Cactus: Algorithms for genome multiple sequence alignment
نویسندگان
چکیده
منابع مشابه
Fast A Algorithms for Multiple Sequence Alignment
The multiple alignment of the sequences of DNA and proteins is applicable to various important elds in molecular biology. Although the approach based on Dynamic Programming is well-known for this problem, it requires enormous time and space to obtain the optimal alignment. On the other hand, this problem corresponds to the shortest path problem and the A algorithm, which can e ciently nd the sh...
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Proteins or genes that have similar sequences are likely to perform the same function. One of the most widely used techniques for sequence comparison is sequence alignment. Sequence alignment allows mismatches and insertion/deletion, which represents biological mutations. Sequence alignment is usually performed only on two sequences. Multiple sequence alignment, is a natural extension of two-se...
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An ever-increasing number of biological modeling methods depend on the assembly of an accurate multiple sequence alignment (MSA). These include phylogenetic trees, profiles, and structure prediction. Assembling a suitable MSA is not, however, a trivial task, and none of the existing methods have yet managed to deliver biologically perfect MSAs. Many of the algorithms published these last years ...
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Sequence alignment is an important tool for describing relationships between sequences. Many sequence alignment algorithms exist, differing in efficiency, and in their models of the sequences and of the relationship between sequences. The focus of this thesis is on algorithms for the optimal alignment of two or three sequences of biological data, particularly DNA sequences. The algorithms are d...
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ژورنال
عنوان ژورنال: Genome Research
سال: 2011
ISSN: 1088-9051
DOI: 10.1101/gr.123356.111