C34, a Membrane Fusion Inhibitor, Blocks HIV Infection of Langerhans Cells and Viral Transmission to T Cells
نویسندگان
چکیده
منابع مشابه
C34, a membrane fusion inhibitor, blocks HIV infection of langerhans cells and viral transmission to T cells.
Development of topical microbicides that prevent sexual transmission of HIV is an active area of investigation. The purpose of this study was to test the ability of the potent membrane fusion inhibitor C34, an HIV gp41 antagonist, to block HIV infection of human Langerhans cells (LCs) in an epithelial environment that mimics a major route of HIV infection. We incubated freshly isolated epiderma...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2007
ISSN: 0022-202X
DOI: 10.1038/sj.jid.5700736