منابع مشابه
Expression of c-MET in Invasive Meningioma
BACKGROUND Meningiomas show high recurrence rates even after curative tumor removal. The invasiveness of meningiomas may contribute to their high recurrence rates. Recently, c-MET and hepatocyte growth factor (HGF) have been reported to be involved in cancer invasion. METHODS We examined the immunohistochemical expression of c-MET and HGF in 100 cases of patients with meningiomas who have und...
متن کاملExpression of the c-Met Proteins in Malignant Skin Cancers.
BACKGROUND The expression of c-Met is substantially elevated in most malignant human cancers. We therefore searched for c-Met expression and compared the expression level among malignant skin cancers. OBJECTIVE The aim of this study was to determine the c-Met expression pattern and the protein expression level in selected malignant cutaneous tumors. METHODS G361 cells (malignant melanoma ce...
متن کاملTumor hypoxia and expression of c-met in cervical cancer.
OBJECTIVES Hypoxia enhances malignant progression by promoting the development of metastases and increasing invasiveness. One key regulator that controls growth, invasion and metastasis in cancer cells is the growth factor receptor c-met. The aim of this study, therefore, was to investigate the expression of the c-met protooncogene in cervical cancers in relation to intratumoral hypoxia levels ...
متن کاملPrognostic significance of c-Met expression in glioblastomas.
BACKGROUND The authors investigated whether expression of c-Met protein in glioblastomas is associated with overall survival and biologic features representing tumor invasiveness in patients with glioblastomas. METHODS Paraffin-embedded specimens of glioblastomas from 62 patients treated in a single institution were assessed by immunohistochemical (IHC) analysis of c-Met expression. On the ba...
متن کاملSoluble c-Met Is a Reliable and Sensitive Marker to Detect c-Met Expression Level in Lung Cancer
c-Met has been demonstrated as an attractive target in lung cancer therapy. Current studies showed that detection of c-Met status in tumor is critical in Met-targeted therapy. However not all patients are suitable for tissue sample collection. It is important to discover novel surrogate markers to detect c-Met status. In the study, soluble c-Met (s-Met) in plasma from 146 Chinese lung cancer pa...
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ژورنال
عنوان ژورنال: The American Journal of Pathology
سال: 2001
ISSN: 0002-9440
DOI: 10.1016/s0002-9440(10)64096-5